Tanzin Nippun Sharmin, However, its potential as an anticancer agent against human cancers is still poorly studied and understood. A bezoar is a mass found trapped in the gastrointestinal system, though it can occur in other locations. A porcupine’s diet is wide, varied, and a little hard to digest. Google Scholar, Khan FAY, Nasir MMH, Jalal T, Razali S, Hassan H, Asuhaimi FA, Wahab RA (2017) In vitro evaluation of porcupine bezoar extracts as anticancer agent on A549—a preliminary study. 3 No. However, its toxicity profile has never been thoroughly ascertained to confirm its safe nature as an efficacious traditional medicine in the treatment of cancer as well as other ailments. 1 (2017): Special Issue: Enhancing Academic and Research Quality, CYTOTOXICITY OF LEUKEMIC CELLS BY NYPA FRUTICANS THROUGH REGULATION OF ADIPONECTIN EXPRESSION, INTERNATIONAL JOURNAL OF ALLIED HEALTH SCIENCES: Vol. https://www.thestar.com.my/opinion/online-exclusive/behind-the-cage/2015/06/12/not-a-miracle-cure/, http://www.animalinfo.org/country/malaysia.html, http://www.enanyang.my/news/20160512/%E7%AE%AD%E7%8C%AA%E6%9E%A3%E4%B9%8B%E8%BF%B7%E6%80%9D%E5%88%98%E6%99%93%E8%88%AA/, http://www.iucnredlist.org/details/10749/0, https://www.thestar.com.my/news/nation/2015/08/05/medicine-shops-claim-wildlife-products-a-cureall/#Zv1MlFF3CiX0VwqB.99, https://doi.org/10.1007/s13596-019-00370-4. The selling price of the porcupine bezoar in Malaysia market is around RM300–RM1000 for 500 mg. Natural antibodies 712 likes. The star online (Newspaper)—behind the cage. UMMU AFIFAH FADZIR, Tara Jalal, Ng Chiew Hoong participated in the design of the study and performed the statistical analysis. Chu Shan Tan. Porcupine dates are also known as porcupine bezoar, a phytobezoar that is formed from the partly digested plant materials or herbs in the stomach of Himalayan porcupine (Hystrix brachyura) [8, 10]. The bezoar itself is a medical illness (gastrolith) for porcupines and needs to be surgically removed for the porcupine to survive. known as porcupine bezoar, a phytobezoar that is formed from the partly digested plant materials or herbs in the stomach of Himalayan porc( Hystrix brachyura )[8, Abstract. One of the traditional folk medicine in the Malaysia is using porcupine bezoar. Porcupine Bezoar is believed to have medicinal value is very high to the extent that it is called the king of herbs. Porcupine Bezoar stone is a type of globular stone-like mass occasionally Produced in a porcupine’s internal body. Google Scholar, Wong LP, AbuBakar S (2013) Health beliefs and practices related to dengue fever: a focus group study. Contact Mr.Syaiful +6281389891852 , +601116377848 Porcupine Bezoar Medicinal Values According to Chinese medicine records, in tradition, Porcupine Bezoar had been used as medicine by hill tribes in Southern China and South-East Asia. A case report [ 43 ] has explained that porcupines which had bezoars suffered clinical signs of weight loss, diarrhea, and depression. Azir Salleh, Retrieved from https://www.thestar.com.my/news/nation/2015/08/05/medicine-shops-claim-wildlife-products-a-cureall/#Zv1MlFF3CiX0VwqB.99, Wang DQH, Carey MC (2014) Therapeutic uses of animal biles in traditional Chinese medicine: an Ethnopharmacological, biophysical chemical and medicinal review. Porcupine Bezoar Medical Value According to Chinese medicine records, our ancestors and some aborigines have knowledge on the medicinal values of the porcupine bezoar. Fatimah Opeyemi Roheem, Ridhwan Abdul Wahab. The materials were collected by Loh Yean Chun. ATHIRAH ROSDI, Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. ANTI-PROLIFERATIVE PROPERTY OF PORCUPINE BEZOAR EXTRACT ON MELANOMA (A375). Retrieved from http://www.orientaldaily.com.my/s/74980, Liu XH (2016) The mystery of porcupine bezoar (箭猪枣之迷思). Alaina Yuhanis Firus Khan, JOURNAL OF BIOMEDICAL AND CLINICAL SCIENCES, 1 (Special Issue). Suppliyer porcupine stone / porcupine bezoar. It is herbivore. The IC50 result for A375 was found to be 10.1 µg/mL ± 0.17. Ridzwan Hashim, Shaida Fariza Sulaiman, In summary, no, there there is no clinical evidence that Porcupine Bezoar cures cancer or other serious medical illness. It is said that when a porcupine is wounded or sick, it will look for herbs to heal itself. 1 No. A porcupine bezoar stone is a mass of food found in the stomach believed to treat diabetes, hepatitis, and dengue fever. Habibah Hassan, Retrieved from http://www.guangming.com.my/node/237350, Barroso MDS (2014) The bezoar stone: a princely antidote, the Tavora Sequira Pinto collection-Aporto. Journal metrics 89 days Submission to first decision 200 days Submission to acceptance 16,094 (2019) Downloads. Retrieved from http://www.enanyang.my/news/20160512/%E7%AE%AD%E7%8C%AA%E6%9E%A3%E4%B9%8B%E8%BF%B7%E6%80%9D%E5%88%98%E6%99%93%E8%88%AA/, Lunde D, Aplin K, Molur S (2008) Hystrix brachyura, Malayan Porcupine. Bezoar porcupine benefits in medicine. Learn more about Institutional subscriptions, Bao SH (2014) 重镇化痰可治瘟病-箭猪枣非治百病. Old Chinese medical text had recorded the used of Porcupine Bezoar. Alfi Khatib, https://doi.org/10.1007/s13596-019-00370-4, DOI: https://doi.org/10.1007/s13596-019-00370-4, Over 10 million scientific documents at your fingertips, Not logged in Ancient book of Chinese medicine have been recorded, porcupine bezoar has benefits such as, 1. Genuine Porcupine bezoar is a medically potent and rare animal gall stone that is commonly found in the stomach region of a porcupine. Issue 4, December 2020 View all volumes and issues. Part of Springer Nature. This quick miracle cure is also perceived to cure cancer, epilepsy, and typhoid.This preternatural or morbid concretions formed in the bodies of porcupines are composed of several layers that look like an onion. The bezoar is traditionally used in South East Asia and Europe for the treatment of cancer, poisoning, dengue, typhoid, etc. It was reported as universal medicine in ancient time. Ridhwan Abdul Wahab, * I speak from my own experience. MOHAMMAD FAUZAN ZAINUDIN, This bezoar has been a myth to the locals. Retrieved from http://www.iucnredlist.org/details/10749/0, Mori E, Sforzi A (2013) Structure of phytobezoars found in the stomach of a crested porcupine, Hystrix cristata L., 1758. The widespread use of the bezoar as an alternative medicine for treatment of deadly illnesses in Malaysia was passed down from generations of the multi-diverse ethnicity environment that existed here. Porcupine bezoar (PB) is used in traditional medicine for various medical conditions. Their meat is considered a delicacy in countries such as Thailand, Vietnam, and Malaysia. Orient Pharm Exp Med 19, 131–136 (2019). However, its potential as an anticancer agent against human cancers is still poorly studied and understood. E-ISSN 2550-147X CAS  PubMed Central  It is a molecular biology technique in order to create pores through a cell wall membrane, boost the permeability of the cell membrane, and support chemicals, drugs or DNA to be imported into Hela cells. Google Scholar, Yew PN, Goh BH, Lim YY, Lee WL (2018) Gastrointestinal bezoar stones: current knowledge and future perspective on the potential of plant-derived phytobezoar in cancer treatment. IC50 for DPPH was found to be 0.79 μg/mL ± 0.07. Google Scholar, The Star Online-Newspaper (2015) Medicine shops claim wildlife products a ‘cure-all’. Acta med Hist Adriat 12(1):77–98, Brown V (2015) Not a miracle cure. Dr Yam Mun Fei conceived and supervised the whole project. Later I found out that bezoar is a mass of food, usually from consuming grass and herbs, found trapped in an animal’s stomach system and is historically used in Chinese traditional medicine. However, limited scientific study has been carried out to verify these traditional claims. 1 No. Alfi Khatib, Porcupine bezoars (PBs) are masses of undigested calcareous concretions formed within the gastrointestinal tract. Porcupine bezoar (PB) has been previously reported to possess various medicinal properties. Medicinal value of porcupine date and porcupine bezoar Based on the ancient medical books, porcupine belly, meat and glitch have medical value and are able to treat various diseases. Hence, in this study, porcupine bezoar (PB) aqueous extract was evaluated for … However, its potential as an anticancer agent against human cancers is still poorly studied and understood. It can be organic or inorganic material and you would expect that it won’t be easy to find. 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Jurisdictional claims in published maps and Institutional affiliations of the traditional folk in! Found in the stomach comprising some indigestible substance ingested by the human or animal, in this study, bezoar..., its potential as an anticancer agent Pharmacy and Experimental medicine volume 19, pages131–136 2019! Had recorded the used of porcupine bezoar has benefits such as,.! And consume with warm wine the ic50 result for A375 was found in the stomach of a porcupine ’ diet...